Shen Hanxiao is a female medical migrant worker who works as a gastroenterologist in a top-10 hospital. Lu Zhizhou is a male researcher who is a rising star in the scientific community and the youngest B-level professor at a top university. Lu Zhizhou loved to smile and endured it for a long time, but when Shen Hanxiao was 22 years old, he could not endure it for a second. The thing that Shen Hanxiao regrets most in her life is that she made a vow after the college entrance examination to “never fall in love before the age of 22.” They are married and have a son together.