Almost everyone knows that the first hero of the late Sui Dynasty was Li Yuanba, but few know that the first medical genius was Zhang Yizhen. Zhang Yizhen met a tragic end; despite his martial arts skills reaching the pinnacle, he was first forced to drink the poisonous wine of Emperor Yang of Sui, and then was shot to death by a thousand imperial guards. The reason was that he had saved the life of Emperor Yang's difficult-to-deliver concubine without any reward, which he felt was a great injustice. Doing good and saving two lives, he ended up with such a fate, truly a historic injustice. Later scientific research has proven that the energy of resentment can be powerful.